Fig. 6
From: Characterizing interactions of Leptospira interrogans with proximal renal tubule epithelial cells
Inhibition of the oxidative stress response confers protection to HP-infected TCMK-1 cells. TCMK-1 cells were pre-treated with different inhibitors and infected with either HP or LP strain for 48 h. a Cell viability was determined by crystal violet assay and shown as the mean percentages ± SD of three independent experiments. b Cells were fixed and stained for AIF. Representative confocal images shown nuclear translocation of mitochondrial AIF in HP-infected cells, which is inhibited by the PARP-1 inhibitor, PJ34