Skip to main content

Table 4 Prevalence and mutation profile in katG, inhA and ahpC genes in INH-resistant strains in Kyrgyzstan

From: Mutations of rpoB, katG, inhA and ahp genes in rifampicin and isoniazid-resistant Mycobacterium tuberculosis in Kyrgyz Republic

Gene Codon Amino acid replacement Nucleotide replacement N = 114 (%) N (%)
katG 315 Ser315→Thr AGC → ACC 101 (88.6) 104 (91.2)
Ser315→Asn AGC → AAC 2 (1.7)
Ser315→Arg AGC → CGC 1 (0.9)
inhA 15 inhA T_15 C → T 8 (7) 8 (7)
ahpC 9 AhpC_9 G → A 1 (0.9) 2 (1.8)
12 AhpC_12 C → T 1 (0.9)