Foreign peptide triggers boost in pneumococcal metabolism and growth

BMC Microbiology

Table 2 Proteins upregulated in wildtype strain 110.58 by exposure to ORF 2 ligand peptide FPPQSV

Protein number	Protein name	Function	Ratio^a	q
AJD72675	Afr	1,5-anhydro-D-fructose reductase	infinite^b	0
AJD71621	DivlB	Cell division protein DivIB	7.1	0.004
AJD71961	PyrP	Uracil transporter	3.8	0.01
AJD71716		ASCH domain protein, Predicted RNA-binding protein YhfF, could regulate translation	3.8	0.01
AJD73085		Hypothetical protein, N-ethylammeline chlorohydrolase, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3.8	0.01
AJD71419	CitS	Sensor protein	2.6	0.01
AJD71122	RibE	Riboflavin synthase	2.3	0.01
AJD71434	trmB	tRNA (guanine-N(7)-)-methyltransferase	2.3	0.01
AJD71098		Hypothetical protein, transcriptional activator, Rgg/GadR/MutR family	1.7	0.02
AJD71572		Hypothetical protein	1.4	0.05
AJD71120	RibH	6,7-dimethyl-8-ribityllumazine synthase	1.4	0.04

For the complete dataset for the wild type and ΔORF 2 mutant see Additional file 6: Table S5, Additional file 7: Table S6, Additional file 8: Table S7, Additional file 9: Table S8
^aRatio represents the fold increase in the protein in the presence of peptide FPPQSV compared to in its absence
^bThe value in the absence of peptide was 0 so fold increase in the presence of peptide could not be calculated

ISSN: 1471-2180