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Table 2 MIC of in vitro combinations of antibiotics by the checkerboard broth microdilution method

From: msaABCR operon is involved in persister cell formation in Staphylococcus aureus

 

Minimum inhibitory concentration (μg/mL)

USA300 LAC

msaABCR

Complementation

DAP / RIF

0.0312 / 0.0078

0.0156 / 0.0039

0.0312 / 0.0078

VAN / RIF

0.156 / 0.0075

0.039 / 0.0075

0.156 / 0.0075

LIN / RIF

0.156 / 0.0037

0.156 / 0.00094

0.156 / 0.0037

DAP / GEN

0.0195 / 1.25

0.312 / 1.25

0.0195 / 1.25

VAN / GEN

0.312 / 1.25

0.312 / 1.25

0.312 / 1.25

LIN / GEN

0.3125 / 2.5

0.039 / 2.5

0.3125 / 2.5

  1. DAP: daptomycin, VAN: vancomycin, RIF: rifampicin, LIN: linezolid, GEN: gentamicin