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Table 2 Identified plasmid and chromosome-encoded virulence genes and other genetic features of O145:H25 and other EHEC genomes

From: Genome sequencing and comparative genomics of enterohemorrhagic Escherichia coli O145:H25 and O145:H28 reveal distinct evolutionary paths and marked variations in traits associated with virulence & colonization

Strains O145:H25 O145:H28 O26:H11 O103:H2 O111:HNM O157:H7 O165:H25
CFSAN004176 CFSAN004177 RM13514 RM13516 11,365 12,009 11,128 Sakai 2012C-4227
chromosome-encoded
aidA-I - - 2 (1) 3 (3) 2 2 (1) 1 1 -
astA 1 1 1 1 1 - 1 1 1
bor (iss) 1 1 1 - 2 1 1 2 1
eae type β β γ γ β ε θ γ ε
efa1 2 (1) 2 (+/−) 1 1 2 1 (+/−) 1
ehaA 1 1 1 1 1 1 1 1 1
espI 1 1 1 - - 1 - - 1
gad 1 1 1 - 1 1 1 1 1
iee (+/−) (+/−) 1 1 1 1 1 1 -
iha - - 1 1 2 - 1 1 -
lpf cluster 1 1 1 (1) 1 2 1 2 2 (1) 1
pagC - - - 1 - 2 1 1 -
sod (Cu/Zn) 1 1 2 2 - 2 2 2 1
stx genes stx 2a stx 2a stx 2a stx 2a stx 1a stx 1a + stx 2a stx 1a + stx 2a stx 1a + stx 2a stx 1a + stx 2a
tir 1 1 1 1 1 1 1 1 1
plasmid-encoded
cba 1 1 - - - - - - -
cma 1 1 - - - - - - -
ecf - - 1 1 1 1 1 1 1
ehxA subtype E E C C C F C B C
espI 1 1 - - - - - - -
espP - - 1 - - - (+/−) 1 1
katP - - - - 1 - - 1 1
sfp 1 1 - - - - - - 1
sta1 1 1 - - - - - - -
stcE - - - 1 - 1 - 1 -
toxB - - 1 - 1 - - 1 -
  1. present (≥ 90% identity, ≥ 80% gene coverage); −, absent; (+/−), partial (≥ 90% identity, 10–80% coverage);
  2. numbers in parentheses indicate pseudogene(s)