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Table 2 Identified plasmid and chromosome-encoded virulence genes and other genetic features of O145:H25 and other EHEC genomes

From: Genome sequencing and comparative genomics of enterohemorrhagic Escherichia coli O145:H25 and O145:H28 reveal distinct evolutionary paths and marked variations in traits associated with virulence & colonization

Strains

O145:H25

O145:H28

O26:H11

O103:H2

O111:HNM

O157:H7

O165:H25

CFSAN004176

CFSAN004177

RM13514

RM13516

11,365

12,009

11,128

Sakai

2012C-4227

chromosome-encoded

  aidA-I

-

-

2 (1)

3 (3)

2

2 (1)

1

1

-

  astA

1

1

1

1

1

-

1

1

1

  bor (iss)

1

1

1

-

2

1

1

2

1

  eae type

β

β

γ

γ

β

ε

θ

γ

ε

  efa1

2 (1)

2

(+/−)

1

1

2

1

(+/−)

1

  ehaA

1

1

1

1

1

1

1

1

1

  espI

1

1

1

-

-

1

-

-

1

  gad

1

1

1

-

1

1

1

1

1

  iee

(+/−)

(+/−)

1

1

1

1

1

1

-

  iha

-

-

1

1

2

-

1

1

-

  lpf cluster

1

1

1 (1)

1

2

1

2

2 (1)

1

  pagC

-

-

-

1

-

2

1

1

-

  sod (Cu/Zn)

1

1

2

2

-

2

2

2

1

  stx genes

stx 2a

stx 2a

stx 2a

stx 2a

stx 1a

stx 1a + stx 2a

stx 1a + stx 2a

stx 1a + stx 2a

stx 1a + stx 2a

  tir

1

1

1

1

1

1

1

1

1

plasmid-encoded

  cba

1

1

-

-

-

-

-

-

-

  cma

1

1

-

-

-

-

-

-

-

  ecf

-

-

1

1

1

1

1

1

1

  ehxA subtype

E

E

C

C

C

F

C

B

C

  espI

1

1

-

-

-

-

-

-

-

  espP

-

-

1

-

-

-

(+/−)

1

1

  katP

-

-

-

-

1

-

-

1

1

  sfp

1

1

-

-

-

-

-

-

1

  sta1

1

1

-

-

-

-

-

-

-

  stcE

-

-

-

1

-

1

-

1

-

  toxB

-

-

1

-

1

-

-

1

-

  1. present (≥ 90% identity, ≥ 80% gene coverage); −, absent; (+/−), partial (≥ 90% identity, 10–80% coverage);
  2. numbers in parentheses indicate pseudogene(s)