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Table 4 List of randomly chosen bacterial IMPase-like proteins that are most likely wrongly annotated with a focus on HolPases. All proteins have been compared to the five IMPase-like proteins in C. glutamicum and reannotated according to the detected motifs

From: Sequence-based identification of inositol monophosphatase-like histidinol-phosphate phosphatases (HisN) in Corynebacterium glutamicum, Actinobacteria, and beyond

Organism GI-number current annotation protein with highest similarity in C. glutamicum presence of expected motifs similarity to HisN Cg (BlastP score) [bits] new functional assignment
Class 1
Pseudomonas pseudoalcaligenes 489546409 IMPase HisN Cg yes 117 HisN
Rudaea cellulosilytica 648601632 IMPase HisN Cg yes 108 HisN
Marinobacter psychrophilus 860341079 IMPase HisN Cg yes 110 HisN
Rubrobacter radiotolerans 627778235 FBPase- or IMPase HisN Cg yes 123 HisN
Class 2
Streptosporangium roseum 502655523 IMPase HisN Cg no 120 -
Rubrobacter xylanophilus 499884516 IMPase HisN Cg no 120 -
Class 3
Sediminibacterium salmoneum 739492005 HolPase SuhB Cg yes 102 SuhB
Flavihumibacter solisilvae 743029970 HolPase SuhB Cg yes 91 SuhB
Desulfatibacillum aliphaticivorans 654864062 HolPase SuhB Cg yes 102 SuhB
Leptospirillum ferriphilum 738123182 HolPase SuhB Cg yes 89 SuhB