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Table 3 Regression analysis between gut microbiota and BMI levels

From: Comparative analysis of gut microbiota associated with body mass index in a large Korean cohort

Overweight vs. Normal Age- and sex- adjusted Multivariate adjusted
Coefficienta Adj. P valueb Coefficienta P value Adj. P valueb
 Cyanobacteria YS2c 0.618 2.63 × 10−9 0.035 0.700 1
Desulfovibrio d 0.435 9.08 × 10−5 −0.101 0.273 1
 Bacteroidales unknown family unknown genusd 0.403 2.48 × 10−4 0.314 0.001 0.068
 Paraprevotellaceae CF231c 0.360 4.58 × 10−4 0.463 2.13 × 10 −7 1.51 × 10 −5
Acidaminococcus d 0.331 0.002 −0.073 0.403 1
 Lactobacillales unknown family unknown genusc 0.174 0.031 0.080 0.333 1
Lactococcus e 0.152 0.042 0.099 0.064 1
Eggerthella e −0.155 0.005 −0.103 0.022 1
Obese vs. Normal
Acidaminococcus d 0.498 3.90 × 10−8 0.378 2.89 × 10 −5 0.002
 Paraprevotellaceae CF231c 0.463 7.32 × 10−6 0.284 0.003 0.181
Megasphaera e 0.443 1.79 × 10−5 0.355 0.002 0.146
Mitsuokella c 0.302 0.034 0.217 0.013 0.946
Eggerthella e −0.162 0.003 −0.073 0.356 1
 Christensenellaceae unknown genusd −0.152 0.031 −0.055 0.003 0.230
 Clostridiales unknown family unknown genus −0.063 0.004 −0.063 5.24 × 10 −5 0.004
Obese vs. Overweight
Acidaminococcus d 0.329 0.001 0.504 2.64 × 10 −8 1.87 × 10 −6
Mitsuokella c 0.271 0.007 0.381 1.10 × 10 −6 2.61 × 10 −5
Akkermansia −0.225 0.038 −0.225 0.001 0.038
 Christensenellaceae unknown genusd −0.179 0.003 −0.170 0.020 0.126
Adlercreutzia 0.139 0.007 0.139 9.34 × 10 −5 0.007
  1. aCoefficient (log2 ratio) driven by zero-inflated Gaussian mixture model (fitZig) using metageomeSeq package
  2. bApplied by Bonferroni multiple comparison correction
  3. cAdditionally adjusted for fat and total calorie intake
  4. dAdditionally adjusted for fiber and total calorie intake
  5. eAdditionally adjusted for carbohydrate and total calorie intake
  6. Coefficient with Adj. P value < 0.05 shown in italic