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Table 3 rLogFC values for genes upregulated in human urine. BLAST results of hypothetical proteins are represented in parentheses

From: DFI-seq identification of environment-specific gene expression in uropathogenic Escherichia coli

Genes upregulated during growth in human urine compared to LB

Protein

Number of genes in operon

rLogFC

ybdL

Aminotransferase

1

2.453653

ybdH

Hypothetical protein (oxidoreductase)

1

2.351791

metE

5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase

1

2.285647

metR

DNA-binding transcriptional dual regulator for metE and MetH

1

2.236911

yjaB

Hypothetical protein (acetyltransferase)

1

2.137446

metA

Homoserine O-succinyltransferase

1

2.033752

argC ;

argB

N-acetyl-gamma-glutamyl-phosphate reductase;

Acetylglutamate kinase

2

2.026239

metF

5,10-methylenetetrahydrofolate reductase

1

2.010415

argE

Acetylornithine deacetylase

1

1.957286

ilvY

IlvY DNA-binding transcriptional dual regulator

1

1.947862

argD

bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase

1

1.91199

yibI

Hypothetical protein

1

1.905502

artJ

Arginine-binding periplasmic protein 2

1

1.808872

argG

Argininosuccinate synthase

1

1.797071

ilvG ;

ilvM

Acetolacetate synthase 2 catalytic subunit; acetolactate synthase 2 regulatory subunit

2

1.752627

yifB ;

UTI89_C4323

predicted ATP-dependent protease;

hypothetical protein

2

1.711417

ydcX

Hypothetical protein (membrane protein)

1

1.634447

UTI89_C2996;

UTI89_C2997;

UTI89_C2998;

yfdN1;

UTI89_C3000

bacteriophage V crossover junction endodeoxyribonuclease;

hypothetical protein;

bacteriophage V DNA adenine methylase;

hypothetical protein;

hypothetical protein

5

1.618326

Crl

DNA-binding transcriptional regulator Crl

1

1.554786

potF

putrescine ABC transporter substrate-binding protein

1

1.529378

metJ

transcriptional repressor protein MetJ

1

1.513308

yibH

Hypothetical protein (membrane protein)

1

1.511398

UTI89_C2260

Hypothetical protein

1

1.503588

UTI89_C0254 ;

UTI89_C0255;

UTI89_C0256

Hypothetical protein;

Hypothetical protein (peptidase C39);

Hypothetical protein

3

1.502547