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Table 3 Statistically significant parameters obtained by multiple regression analysis, and by correlations between experimental and calculated values

From: Antimicrobial structure activity relationship of five anthraquinones of emodine type isolated from Vismia laurentii

Parameters pH 7 pH 6 pH 5
coef ± errSt ICf 95% ICs95% P coef ± errSt ICf 95% ICs95% P coef ± errSt ICf 95% ICs95% P
Const 1.671 ± 0.072 1.531 1.813 0 2.410 ± 0.156 2.104 2.716 0 2.197 ± 0.206 1.792 2.601 0
Log Ko/w 0.488 ± 0.020 0.448 0.528 0 NS - - - NS - - -
MW (mol/g) NS - - - −0.077 ± 0.009 −0.094 −0.059 0 0.092 ± 0.012 −0.116 −0.069 0
HA 0.774 ± 0.031 0.714 0.835 0 1.321 ± 0.142 1.043 1.598 0 1.620 ± 0.187 1.254 1.987 0
Polarz −0.147 ± 0.006 −0.158 −0.135 0 0.537 ± 0.065 0.409 0.665 0 0.642 ± 0.086 0.473 0.810 0
R2 Model   0.995     0.943     0.936   
SSE Model   0.001     0.015     0.026   
  1. coef ± errSt parameters coefficient, P probability of kindness of the equation, Const constancy, MW molecular weight, Log K o/w (or Log P) partition coefficient, Polarz polarizability, HA hydrogen bond acceptor, NS non significative, IC f 95% and IC s 95% inferior (ICf) and superior (ICs) confidence interval, correlation values: R2 model and SSE model