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Table 2 Minimal Inhibitory Concentration (MIC) of diselenides against different microorganisms

From: Diphenyl diselenide derivatives inhibit microbial biofilm formation involved in wound infection

MIC (mg/L)

9

10

11

10c

10d

10e

Positive controla

Staphylococcus aureus

>250

125

250

>250

>250

31.25

7.8

Staphylococcus epidermidis

15.62

3.9

>250

>250

7.8

7.8

0.18

Streptococcus pyogenes

15.62

7.8

31.25

>250

15.62

31.25

2.19

Streptococcus pneumoniae

>250

125

>250

250

>250

>250

0.45

Pseudomonas aeruginosa

>250

>250

>250

>250

250

>250

1.5

Candida albicans

31.25

62.5

125

>250

>250

>250

0.25

  1. MIC was evaluated by standardized CLSI methods
  2. aThe positive control for Gram-positive and Gram-negative bacteria was gentamicin and Fluconazole for Candida albicans