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Table 1 Comparison of the Line Probe Assay with the Reference PCR for bacterial meningitis in CSF samples

From: Evaluation of the line probe assay for the rapid detection of bacterial meningitis pathogens in cerebrospinal fluid samples from children

LPA results Reference PCR results
(n)
 
  Negative Sp Hib Men Hi lytA Eq hpd Eq ctrA Eq Total
Negative 380 24 1 6 2 12 4 2 431
Sp 30 92 0 0 0 5 0 0 127
Hib 15 3 35 0 0 0 0 0 53
Men 4 2 0 35 0 0 0 0 41
16S DNA 92 2 0 0 0 1 0 0 95
Double banding Sp or Hib 0 0 1 1 0 0 0 0 2
Double banding Hib or Men 1 1 0 0 0 0 0 0 2
Not done 73 7 3 5 1 1 0 0 90
Total 595 131 40 47 3 19 4 2 841
  1. LPA line probe assay, Sp Streptococcus pneumoniae, Hib H. influenzae type b, Men N. meningitidis, Hi non-typeable H. influenzae, lytA Eq equivocal for ltyA, hpd Eq equivocal for hpd, ctrA Eq equivocal for ctrA