Table 2 Gene expression changes in early stationary phase, 5-azacytidine-treated Escherichia coli cells
Gene ID | Name | Description | fold-change (log2) | p |
|---|---|---|---|---|
b1557 | cspB | Cold shock protein, Qin prophage; cold shock inducible | 3.40 | 7.28E-04 |
b2699 | recA | Multifunctional DNA recombination and repair protein; ssDNA-dependent ATPase; synaptase; ssDNA and dsDNA binding protein forming filaments; ATP-dependent homologous DNA strand exchanger; recombinase A; LexA autocleavage cofactor | 2.53 | 4.87E-05 |
b3175 | secG | SecYEG inner membrane translocon secA-interacting subunit; preprotein translocase secAYEG subunit | 2.43 | 3.43E-04 |
b4177 | purA | Adenylosuccinate synthase, purine synthesis | 2.37 | 6.70E-04 |
b4314 | fimA | Fimbrin type 1, major structural subunit; phase variation | 2.11 | 1.33E-03 |
b3231 | rplM | 50S ribosomal subunit protein L13; binds Zn(II) | 2.00 | 1.12E-03 |
b3186 | rplU | 50S ribosomal subunit protein L21 | 1.92 | 5.10E-04 |
b3230 | rpsI | 30S ribosomal subunit protein S9 | 1.77 | 3.95E-04 |
b3739 | atpI | ATP synthase, membrane-bound accessory factor | 1.68 | 7.67E-04 |
b0406 | tgt | tRNA-guanine transglycosylase; queuosine biosynthesis; zinc metalloprotein | 1.66 | 1.97E-03 |
b3735 | atpH | ATP synthase subunit delta, membrane-bound, F1 sector | 1.66 | 1.70E-03 |
b4200 | rpsF | 30S ribosomal subunit protein S6; suppressor of dnaG-Ts | 1.64 | 2.18E-03 |
b3409 | feoB | Putative ferrous iron permease with GTP-binding domain | 1.62 | 3.37E-03 |
b3810 | yigA | DUF484 family protein, function unknown | 1.57 | 2.66E-03 |
b0926 | ycbK | Periplasmic M15A family non-protease, function unknown | 1.56 | 8.53E-04 |
b0927 | ycbL | Glyoxalase II homolog, function unknown | 1.56 | 3.57E-03 |
b3704 | rnpA | RNase P, C5 protein component; involved in tRNA and 4.5S RNA-processing | 1.56 | 2.51E-03 |
b3342 | rpsL | 30S ribosomal subunit protein S12; RNA chaperone | 1.54 | 2.60E-05 |
b4238 | nrdD | Ribonucleoside-triphosphate reductase; class III anaerobic ribonucleotide reductase | 1.54 | 1.83E-03 |
b1147 | ymfL | Function unknown, e14 prophage | 1.53 | 1.66E-03 |
b2150 | mglB | D-galactose-, D-glucose-binding protein, periplasmic; substrate recognition for transport and chemotaxis; binds calcium | 1.45 | 2.24E-03 |
b4148 | sugE | Multidrug efflux pump; overexpression resistance to cetylpyridinium | 1.44 | 1.22E-03 |
b3983 | rplK | 50S ribosomal subunit protein L11; kasugamycin sensitivity | 1.44 | 2.33E-03 |
b0118 | acnB | Aconitate hydratase 2; aconitase B; 2-methyl-cis-aconitate hydratase; iron-sulfur cluster; monomeric | 1.42 | 1.80E-03 |
b0407 | yajC | SecDFyajC membrane secretion complex subunit; assists the SecYE translocon to interact with SecA and export proteins | 1.41 | 2.23E-03 |
b3357 | crp | cAMP-activated global transcription factor; mediator of catabolite repression; CRP; CAP | 1.40 | 1.49E-04 |
b2796 | sdaC | L-serine:H+ symport permease, threonine-insensitive | 1.40 | 1.84E-03 |
b3637 | rpmB | 50S ribosomal subunit protein L28 | 1.38 | 9.87E-05 |
b3508 | yhiD | Predicted Mg(2+) transport ATPase, MgtC family, function unknown; inner membrane protein | 1.35 | 2.62E-03 |
b3339 | tufA | Translation elongation factor EF-Tu 1; GTP-dependent binding of aa-tRNA to the A-site of ribosomes; has intrinsic GTPase activity when bound to kirromycin | 1.33 | 3.21E-03 |
b3985 | rplJ | 50S ribosomal subunit protein L10; streptomycin resistance | 1.30 | 3.36E-03 |
b0428 | cyoE | Cytochrome o oxidase protoheme IX farnesyltransferase subunit | 1.26 | 8.29E-04 |
b0174 | ispU | Undecaprenyl pyrophosphate synthase; dimeric | 1.22 | 1.14E-04 |
b0756 | galM | Aldose 1-epimerase, type-1 mutarotase; galactose mutarotase; monomeric | 1.21 | 1.92E-03 |
b0946 | zapC | FtsZ stabilizer | 1.19 | 1.47E-04 |
b2279 | nuoK | NADH:ubiquinone oxidoreductase subunit K, complex I; NADH dehydrogenase I | 1.15 | 2.64E-04 |
b0388 | aroL | Shikimate kinase II | 1.12 | 6.85E-04 |
b4237 | nrdG | Ribonucleotide reductase activase, generating glycyl radical; contains iron; binds NrdD tightly | 1.11 | 4.09E-04 |
b4016 | aceK | Isocitrate dehydrogenase kinase/phosphatase | 1.11 | 1.10E-03 |
b1847 | yebF | Extracellular Colicin M immunity family protein; function unknown | 1.08 | 5.59E-04 |
b3961 | oxyR | Oxidative and nitrosative stress transcriptional regulator | 1.08 | 2.03E-03 |
b0463 | acrA | AcrAB-TolC multidrug efflux pump; additionally dye, detergent, solvent resistance; membrane-fusion lipoprotein | 1.06 | 2.36E-04 |
b3255 | accB | Acetyl-CoA carboxylase, biotin carboxyl carrier protein; BCCP; homodimeric | 1.05 | 6.41E-04 |
b0083 | ftsL | Cell division and growth, membrane protein | 1.01 | 9.70E-04 |
b1195 | ymgE | UPF0410 family predicted inner membrane protein; function unknown | −1.01 | 2.15E-03 |
b0255 | insN' | Pseudogene reconstruction, fused IS911 transposase AB | −1.08 | 2.42E-04 |
b4107 | yjdN | Metalloprotein superfamily protein, function unknown | −1.30 | 4.90E-04 |
b1223 | narK | Nitrate/nitrite antiporter; promotes nitrite extrusion and uptake | −1.31 | 3.47E-03 |
b1739 | osmE | Osmotically inducible lipoprotein, function unknown | −1.46 | 1.01E-03 |
b0836 | bssR | Repressor of biofilm formation by indole transport regulation; global regulator. e.g. of AI-2 transport and motility genes | −1.52 | 5.23E-05 |
b1795 | yeaQ | UPF0410 family protein, function unknown | −1.56 | 1.65E-03 |
b2414 | cysK | Cysteine synthase A, O-acetylserine sulfhydrylase A; homodimeric; selenate, azaserine, chromate resistance; alkali-inducible, sulfate starvation-inducible protein SSI5; cysteine desulfhydrase | −1.58 | 2.86E-03 |
b0806 | mcbA | Stimulates colanic acid mucoidy, YhcN family, periplasmic; suppresses biofilm formation; repressed by McbR | −1.71 | 5.11E-04 |
b2425 | cysP | Thiosulfate-binding protein, periplasmic | −1.84 | 1.90E-04 |
b0506 | allR | Repressor for all (allantoin) and gcl (glyoxylate) operons; glyoxylate-inducible | −1.93 | 1.10E-03 |
b0456 | ybaA | DUF1428 family protein | −1.98 | 2.30E-03 |