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Table 1 Mode of action of different classes of antibiotics

From: Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

Mode of action Action Antibiotics
Cell wall synthesis inhibitors:
Inhibition of penicillin binding proteins (PBPs)
bactericidal ß-lactam-antibiotics
Penicillin-derivatives:
Ampicillin, Carbenicillin
Cephalosporin-derivatives:
Cefalexin
DNA and protein synthesis inhibitors:
Inhibition of topoisomerase
bactericidal Fluoroquinolones
Ofloxacin, Ciprofloxacin
Protein synthesis inhibitors:
Inhibition of 30s subunit
bacteriostatic Tetracycline derivatives
Tetracycline, Doxycycline
Protein synthesis inhibitors:
Inhibition of 30s subunit
bactericidal Aminoglycosides
Kanamycin, Streptomycin