Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species

Table 2 Fluorescent cell percentage of yeasts treated with CaThi^a

Yeasts species	Sample	Cell number viewed in DIC	Cell number viewed in fluorescence	% of fluorescence cells^b
C. albicans	control	62.0 ± 9.3	0.6 ± 0.8	0.9
C. albicans	CaThi	20.0 ± 5.0	16.6 ± 5.3	83.0
C. tropicalis	control	41.2 ± 4.2	0.8 ± 1.3	1.9
C. tropicalis	CaThi	9.8 ± 4.9	4.8 ± 4.6	48.9
C. parapsilosis	control	79.2 ± 12.1	0	0
C. parapsilosis	CaThi	18.2 ± 5.4	6.2 ± 1.4	34.0
C. pelliculosa	control	23.8 ± 3.5	0	0
C. pelliculosa	CaThi	7.2 ± 1.9	6.6 ± 2.3	91.6
C. buinensis	control	43.6 ± 9.0	0.8 ± 1.3	1.8
C. buinensis	CaThi	13.6 ± 6.2	6.2 ± 1.3	45.5
C. mogii	control	18.6 ± 3.2	0.6 ± 0.8	3.2
C. mogii	CaThi	8.6 ± 2.0	4.4 ± 2.7	51.1

^aCells number determination in five random fields of the DIC and fluorescence views of the samples obtained from Plasma membrane permeabilization assay. The total cell number in DIC of each yeast (in control and test) was assumed as 100 %
^bIndicates significance by the T test (P < 0.05) among the experiments and their respective controls

ISSN: 1471-2180