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Table 3 Quantitative detection of C. perfringens in stool samples from healthy infants and young adults by Amp-qPCR assays targeting 16S rRNA, plc and cpe genes

From: Sensitive quantification of Clostridium perfringens in human feces by quantitative real-time PCR targeting alpha-toxin and enterotoxin genes

Target Infant aged 6 months Young adult
(n = 124) (n = 221)
Bacterial count (log10 bacterial cells/g feces)a Detection rate (%) Bacterial count (log10 bacterial cells/g feces)a Detection rate (%)
16S rRNA gene 6.4 ± 1.3 35 4.8 ± 1.2b 31
plc 6.0 ± 1.5 36 4.8 ± 1.2b 33
cpe 5.9 ± 1.9 10 4.8 ± 0.8 1c
  1. aData are expressed as the means and standard deviations
  2. b p < 0.05 (vs. Infant aged 6 months), Mann–Whitney U test
  3. c p < 0.05 (vs. Infant aged 6 months), Fisher’s exact probability test