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Table 3 Proteins identified in the secretome of C. neoformans collected at 96 hpi from cells grown in Pka1-induced (galactose-containing medium) conditions

From: Secretome profiling of Cryptococcus neoformans reveals regulation of a subset of virulence-associated proteins and potential biomarkers by protein kinase A

GO categoriesa Accession number Protein name Fold changeb Std. Dev.
Carbohydrate catabolic process   
  CNAG_02189 α-Amylase 1.061 0.080
GTP catabolic process   
  CNAG_06125 Translation elongation factor 1 α 0.462 0.555
Carbohydrate metabolic process   
  CNAG_04245 Chitinase 0.621 0.562
  CNAG_06501 1,3-β-glucanosyltransferase 1.101 0.140
  CNAG_01239 Chitin deacetylase 2.659 1.996
  CNAG_02860 Endo-1,3(4)-β-glucanase 3.210 1.665
Protein ubiquitination   
  CNAG_01920 Polyubiquitin 0.509 0.501
ATP hydrolysis coupled proton transport   
  CNAG_05750 ATPase α subunit 1.785 1.765
Dephosphorylation   
  CNAG_02944 Acid phosphatase 0.233 0.061
Oxidation-reduction process   
  CNAG_01019 Cu/Zn superoxide dismutase 0.350 0.142
  CNAG_03465 Laccase 1.000 0.107
Proteolysis   
  CNAG_00919 Carboxypeptidase D 5.770 3.708
Response to stress   
  CNAG_01750 Chaperone >10 >10
Unknown/Unclassified   
  CNAG_04291 Glycosyl-hydrolase 0.989 0.959
  CNAG_00407 Glyoxal oxidase 1.209 0.648
  CNAG_06267 Rds1 protein 2.834 0.518
  CNAG_01653 Cytokine-inducing glycoprotein 2.951 2.753
  CNAG_04753 Lactonohydrolase >10 >10
Hypothetical   
  CNAG_06109 Conserved hypothetical protein 0.463 0.431
  CNAG_05893 Conserved hypothetical protein 1.062 0.307
  CNAG_05312 Conserved hypothetical protein 3.737 2.342
  1. aProteins were categorized based on GO terms associated with their biological classification
  2. bFold change is reported as the average quantification for P GAL7 ::PKA1 vs. WT, ± standard deviation