Chlamydia Outer Protein (Cop) B from Chlamydia pneumoniae possesses characteristic features of a type III secretion (T3S) translocator protein

Table 1 Comparison of putative chaperone binding domains between Chlamydiaceae family members and other T3SS containing Gram-negative bacteria

	P1		P3			P6	Percent identity
CopB (C. pneumoniae)	P	E	L	P	K	P	100 %
CT578 (C. trachomatis serovar D)	P	G	L	P	K	P	52 %
SseC like family protein (C. psittaci)	P	D	L	P	K	P	53 %
TC_0867 (C. muridarum)	P	G	L	P	K	P	50 %
CPE1_0913 (C. pecorum)	P	E	L	T	P	P	53 %
CAB923 (C. abortus S26/3)	P	D	L	P	K	P	54 %
PopB (Y. enterocolitica)	P	A	L	G	R	P	18 %
IpaB (S. dyseteriae)	P	E	L	K	A	P	17 %

Putative chaperone binding domains were identified within the N-terminal regions of orthologous proteins to CopB from C. pneumoniae. P1, P3, P6, represent positions 1, 3, and 6, respectively of the PxLxxP motif. Percent identity refers to amino acid sequence identity comparing full length CopB to full length sequences of orthologous proteins

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