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Table 1 Correlation of antibiotic resistance between class 1 integron-positive and integron-negative of S.aureus

From: Variability in gene cassette patterns of class 1 and 2 integrons associated with multi drug resistance patterns in Staphylococcus aureus clinical isolates in Tehran-Iran

Antibiotics All strains of S.aureus (n = 139) Integron-positive isolates (n = 101) Integron-negative isolates (n = 38) P value
R S R S R S
AK* 43 (31 %) 96 (69 %) 35 (34.7 %) 66 (25.3 %) 8 (21 %) 30 (79 %) 0.088
SXT* 38 (27.3 %) 101 (72.7 %) 34 (33.7 %) 67 (66.3 %) 4 (10.5 %) 34 (89.5 %) 0.004
C* 49 (32.3 %) 90 (64.7 %) 41 (40.6 %) 60 (59.4 %) 8 (21 %) 30 (79 %) 0.024
TE* 78 (56.1 %) 61 (43.9 %) 65 (64.4 %) 36 (35.6 %) 13 (34.2 %) 25 (65.8 %) 0.001
CIP* 56 (40.3 %) 83 (59.7 %) 49 (48.5 %) 52 (51.5 %) 7 (18.4 %) 31 (81.6 %) 0.001
GM* 76 (54.7 %) 63 (45.3 %) 68 (67.3 %) 33 (32.7 %) 8 (21 %) 30 (79 %) <0.001
SPC* 86 (61.9 %) 53 (38.1 %) 73 (72.3 %) 28 (27.7 %) 13 (34.2 %) 25 (65.8 %) <0.001
ATH* 69 (49.6 %) 70 (50.4 %) 62 (61.4 %) 39 (38.6 %) 7 (18.4 %) 31 (81.6 %) <0.001
S* 75 (54 %) 64 (46 %) 61 (60.4 %) 40 (39.6 %) 14 (37 %) 24 (63 %) 0.011
GAT 44 (31.7 %) 95 (68.3 %) 32 (31.7 %) 69 (68.3 %) 12 (31.6 %) 26 (68.4 %) 0.581
OXA 104 (74.8 %) 35 (25.2 %) 76 (75.2 %) 25 (24.8 %) 28 (73.7 %) 10 (26.3 %) 0.505
PG 137 (98.6 %) 2 (1.4 %) 101 (100 %) 0 (0 %) 36 (94.7 %) 2 (5.3 %) 0.073
RP 43 (31 %) 96 (69 %) 31 (30.7 %) 70 (69.3 %) 12 (31.6 %) 26 (68.4) 0.537
LZD 24 (17.3 %) 115 (82.7 %) 20(19.8 %) 81 (80.2 %) 4 (10.5 %) 34 (89.5 %) 0.149
CD 84 (60.4 %) 55 (39.6 %) 65 (64.4 %) 36 (35.6 %) 19 (50 %) 19 (50 %) 0.089
E* 95 (68.3 %) 44 (31.7 %) 78 (77.2 %) 23(22.8 %) 17 (44.7 %) 21 (55.3 %) <0.001
TN 66 (47.5 %) 73 (52.5 %) 46 (45.5 %) 55 (54.5 %) 20 (52.6 %) 18 (47.4 %) 0.289
LEV* 56 (40.3 %) 83 (59.7 %) 49 (48.5 %) 52 (51.5 %) 7 (18.7 %) 31 (81.6 %) 0.001
CRO* 71 (51.1 %) 68 (48.9 %) 66 (65.3 %) 35 (34.7 %) 5 (13.1 %) 33 (86.9 %) <0.001
  1. *: significant values, AK Amikacin, SXT Trimethoprim- Sulfamethoxazole, C Chloramphenicol, TE Tetracycline, CIP Ciprofloxacin, GM Gentamicin, SPC Spectinomycin, ATH Azithromycine, S Streptomycin, GAT Gatifloxacin, OXA Oxacillin, PG Penicillin G, RP Rifampin, LZD Linezolid, CD Clindamycin, E Erythromycin, TN Tobramycin, LEV Levofloxacin, CRO Ceftriaxone; R Resistant, S sensitive