The Neisseria gonorrhoeae Obg protein is an essential ribosome-associated GTPase and a potential drug target

BMC Microbiology

Table 1 Comparison of the amino acid sequences of the N. gonorrhoeae Obg protein with Obg homologs

Organism	Accession number	Protein length	Region aligned	% identity	% similarity
Neisseria gonorrhoeae NCCP11945	B4RQP4	384	1-384	100	100
Neisseria meningitidis MC58	Q9JXE5	384	1-384	98	98
Neisseria lactamica 020-06	E4ZAV0	384	1-384	97	97
Neisseria weaveri LMG 5135	G2DJV3	384	1-384	85	91
Escherichia coli K12	P42641	390	1-344	56	71
Caulobacter crescentus NA1000/CB15N	B8GYI7	354	1-320	52	67
Bacillus subtilis 168	P20964	428	2-328	49	68
Chlamydia trachomatis D/UW-3/Cx	O84423	335	2-335	43	62
Homo sapiens	Q9H4K7*	406	72-364	40	58
Homo sapiens	A4D1E9**	308	77-293	35	52
Saccharomyces cerevisiae 204508	P38860	518	295-488	40	61

*ObgH1 (GTP binding protein 5, GTBP5; mitochondrial ribosome-associated GTPase 2, MTG2)
**ObgH2 (GTP binding protein 10, GTPBP10)

ISSN: 1471-2180