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Table 2 In vitro activity (MIC 50 , MIC 90 , and MIC range, μg/L) and percentage of H. influenzae isolates that were susceptible (S), intermediate (I), or resistant (R) to antibiotic agents during the study period

From: Nasopharyngeal carriage and antimicrobial susceptibility of Haemophilus influenzae among children younger than 5 years of age in Beijing, China

Antibiotics agents Year MIC 50 MIC 90 MIC range S (%) I (%) R (%)
Ampicillin (AMP) 2000 0.19 0.44 0.064–256 96 0 4.0
2002 0.25 1 0.064–256 87 0 13.0
2010 0.75 256 0.064–256 63.0 9.9 27.1
2012 0.75 256 0.064–256 61.2 7.8 31.0
Amoxicillin / clavulanic acid (AMC) 2000 0.5 0.75 0.19–3 100 0 0
2002 0.5 1 0.064–4 100 0 0
2010 0. 5 2 0. 19–3 100 0 0
2012 0.75 3 0. 19–8 97.8 0 2.7
Cefaclor (CFC) 2000 1.5 2 0.5–48 98.0 1.0 1.0
2002 1 2 0.38–48 95.0 2.0 3.0
2010 1.5 16 0.5–128 87.2 5.7 7.1
2012 1.5 12 0.5–256 81.0 6.8 12.2
Cefuroxime (CXM) 2000 0.5 0.75 0.19–4 100 0 0
2002 - - - 99 1.0 0
2010 0.75 1 0.75–4 97.1 2.9 0
2012 0.75 1 0.75–4 91.9 2.7 5.4
Ceftriaxone (CRO) 2000 0.004 0.006 0.002–0.032 100 0 0
2002 - -   99 1.0 0
2010 0.008 0.016 - 100 0 0
2012 0.016 0.047 0.004–0.032    
0.016–0.75 100 0 0     
Tetracycline (TCY) 2000 - - - 60.0 23.0 17.0
2002 - - - 54.0 24.0 22.0
2010 - - - 91.5 7.1 1.4
2012 - - - 94.5 4.1 1.4
Sulfamethoxazole (SXT) 2000 - - - 21.0 0 79.0
2002 - - - 37.0 1.0 62.0
2010 - - - 22.9 1.4 75.7
2012 - - - 28.4 2.7 68.9
Chloramphenicol (CHL) 2000 - - - 93.0 1.0 6.0
2002 - - - 87.0 1.0 12.0
2010 - - - 88.6 11.4 0
2012 - - - 95.9 0 4.1