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Table 3 Effect of mucin (in co-culture with B. bifidum PRL2010) on the transcriptome of B. breve UCC2003

From: Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium

Gene No.

Predicted Function

Level of upregulation (P < 0.001)

Bbr_0161_ nanK

Conserved hypothetical protein in ROK family

4.22

Bbr_0162_ nanE

N-acetylmannosamine-6-phosphate 2-epimerase

5.46

Bbr_0164_ nanB

ABC transport system, solute binding protein

14.08

Bbr_0165_ nanC

ABC transport system, permease protein

11.82

Bbr_0166_ nanD

ABC transport system, ATP-binding protein

18.92

Bbr_0167_ nanF

ABC transport system, ATP-binding protein

22.14

Bbr_0168_ nanA

N-acetylneuraminate lyase

15.17

Bbr_0169_ nagB1

Glucosamine-6-phosphate isomerase

17.77

Bbr_0171_ nanH

Sialidase

7.23

Bbr_0173_ nanR

Transcriptional regulator, GntR family

4.80

Bbr_1247_ nagA2

N-acetylglucosamine-6-phosphate deacetylase

4.59

Bbr_1248_ nagB3

Glucosamine-6-phosphate isomerase

6.08

Bbr_1585_ galE

UDP-Glc-4-epimerase

3.96

Bbr_1586_ nahK

N-acetylhexosamine kinase

3.67

Bbr_1587_ lnbP

Lacto-N-biose phosphorylase

3.19

Bbr_1588

ABC transport system, permease protein

3.34

Bbr_1589

ABC transport system, permease protein

2.88

Bbr_1590

ABC transport system, solute binding protein

8.95

Bbr_1740_ dapA4

Dihydrodipicolinate synthase

9.91

Bbr_1741

Conserved hypothetical protein

8.83

Bbr_1742_ fucP

L-fucose permease

7.81

Bbr_1833_ lacZ7

Beta-galactosidase

4.31

Bbr_1879

PTS system, glucose-specific IIABC component

6.97

Bbr_1880

PTS system, GlcNAc-specific IIBC component

18.15

Bbr_1884_ galT2

Gal-1-phosphate uridylyltransferase

3.86

  1. The cut-off point for the level of up-regulation is 2.5-fold with a P-value of <0.001.