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Table 3 Effect of mucin (in co-culture with B. bifidum PRL2010) on the transcriptome of B. breve UCC2003

From: Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium

Gene No. Predicted Function Level of upregulation (P < 0.001)
Bbr_0161_ nanK Conserved hypothetical protein in ROK family 4.22
Bbr_0162_ nanE N-acetylmannosamine-6-phosphate 2-epimerase 5.46
Bbr_0164_ nanB ABC transport system, solute binding protein 14.08
Bbr_0165_ nanC ABC transport system, permease protein 11.82
Bbr_0166_ nanD ABC transport system, ATP-binding protein 18.92
Bbr_0167_ nanF ABC transport system, ATP-binding protein 22.14
Bbr_0168_ nanA N-acetylneuraminate lyase 15.17
Bbr_0169_ nagB1 Glucosamine-6-phosphate isomerase 17.77
Bbr_0171_ nanH Sialidase 7.23
Bbr_0173_ nanR Transcriptional regulator, GntR family 4.80
Bbr_1247_ nagA2 N-acetylglucosamine-6-phosphate deacetylase 4.59
Bbr_1248_ nagB3 Glucosamine-6-phosphate isomerase 6.08
Bbr_1585_ galE UDP-Glc-4-epimerase 3.96
Bbr_1586_ nahK N-acetylhexosamine kinase 3.67
Bbr_1587_ lnbP Lacto-N-biose phosphorylase 3.19
Bbr_1588 ABC transport system, permease protein 3.34
Bbr_1589 ABC transport system, permease protein 2.88
Bbr_1590 ABC transport system, solute binding protein 8.95
Bbr_1740_ dapA4 Dihydrodipicolinate synthase 9.91
Bbr_1741 Conserved hypothetical protein 8.83
Bbr_1742_ fucP L-fucose permease 7.81
Bbr_1833_ lacZ7 Beta-galactosidase 4.31
Bbr_1879 PTS system, glucose-specific IIABC component 6.97
Bbr_1880 PTS system, GlcNAc-specific IIBC component 18.15
Bbr_1884_ galT2 Gal-1-phosphate uridylyltransferase 3.86
  1. The cut-off point for the level of up-regulation is 2.5-fold with a P-value of <0.001.