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Table 2 Viable count (CFUs; means ± SEM) of H. pylori strains in G. mellonella at 24, 48 and 72 h post-infection

From: Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori

Strains T0 24 h 48 h 72 h
G27 1.1 (±0.06) × 106 3.9 (±0.03) × 106 5.2 (±0.8) × 106 1.6 (±0.3) × 107
G27Δcag A 1.6 (±0.2) × 106 2.8 (±0.06) × 106 4.6 (±0.4) × 106 1.1 (±0.2) × 107
G27Δcag E 1.0 (±0.1) × 106 2.2 (±0.04) × 106 4.0 (±0.6) × 106 9.2 (±0.3) × 106
G27ΔcagPAI 1.2 (±0.3) × 106 2.0 (±0.02) × 106 3.6 (±0.4) × 106 8.6 (±0.2) × 106
60190 1.6 (±0.1) × 106 5.2 (±0.02) × 106 7.8 (±0.1) × 106 1.8 (±0.9) × 107
60190ΔvacA 8.4 (±0.2) × 105 1.9 (±0.04) × 106 3.9 (±0.1) × 106 9.4 (±0.3) × 106
60190ΔcagA 1.2 (±0.1) × 106 2.1 (±0.05) × 106 4.2 (±0.2) × 106 1.2 (±0.3) × 107
60190ΔcagE 1.0 (±0.04) × 106 1.8 (±0.03) × 106 3.4 (±0.4) × 106 1.0 (±0.3) × 107
60190Urease-negative 1.4 (±0.06) × 106 2.6 (±0.2) × 106 4.9 (±0.4) × 106 9.8 (±0.2) × 106
M5 1.3 (±0.04) × 106 2.0 (±0.4) × 106 4.2 (±0.5) × 106 1.2 (±0.2) × 107
M5ggt::aph 1.2 (±0.04) × 106 1.8 (±0.2) × 106 3.6 (±0.6) × 106 9.6 (±0.4) × 106
  1. The number of viable bacteria in infected larvae were determined as described in the Methods section and expressed in CFUs.