Skip to main content

Table 1 Lethal dose 50% of H. pylori strains in Galleria mellonella

From: Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori

  LD50(means ± SEM)*
Strains 48 h 72 h
G27 2.8 (±0.4) × 105 2.4 (±0.2) × 105
G27Δcag A   3.1 (±0.04) × 106
G27Δcag E   2.4 (±0.06) × 106
G27ΔcagPAI   2.0 (±0.01) × 106
60190 6.1 (±0.4) × 105 1.4 (±0.04) × 106
60190ΔvacA   8.2 (±0.04) × 106
60190ΔcagA   9.7 (±0.04) × 106
60190ΔcagE   9.5 (±0.06) × 106
60190Urease-negative   8.7 (±0.04) × 106
M5 12.8 (±0.3) × 105 2.1 (±0.08) × 105
M5 ggt::aph 12.0 (±0.6) × 105 1.0 (±0.1) × 105
  1. *The LD50 values were expressed in Colony Forming Units (CFUs).