Figure 2

Selected GO terms related to "GO: 0052040 modulation by symbiont of host programmed cell death". A greatly simplified directed acyclic graph (DAG) showing key low-level terms describing modulation of programmed cell death in one organism (the host) by another organism (the symbiont) is depicted. A simplified lineage for these terms is shown up to "GO: 0008150 biological_process". Only selected terms are shown, and only a few of the parent-child relationships are depicted; arrows symbolize GO "is_a" and "part_of" relationships (for more information on ontology structure, i.e. "is_a", "part_of", and "regulates", see [13]). Note that "GO: 0052040 modulation by symbiont of host programmed cell death" (denoted by a dark star) and "GO: 0052031 modulation by symbiont of host defense response" (light star) both ultimately exist under the "GO: 0051704 multi-organism process" node. The GO terms shaded with grey represent annotations discussed in the text; GO terms highlighted with broken lines or black serve as reference points for Additional file 1 and Additional file 2, respectively.