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Figure 2 | BMC Microbiology

Figure 2

From: Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

Figure 2

Recruitment of actin to C. caviae GPIC entry sites. HeLa cells were infected with FITC-labelled C. caviae GPIC in the presence or absence of 60 μM INP0341. At 10 minutes p.i. cells were fixed and actin filaments were visualized with Alexa-Fluor 546-phalloidin. (A) Actin remodelling around FITC-labelled bacteria was observed in control cells as well as in cells treated with INP0341 (arrows). (B) Quantification of actin aggregates in the presence or absence of INP0341. The number of actin aggregates per field was divided by the number of cells in the field (n>30). The average and standard deviation from three fields are shown.

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BMC Microbiology

ISSN: 1471-2180

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