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Table 3 Analysis of molecular distances and synonymous and non-synonymous nucleotide substitutions in gene segments 1 and 3, within each gene (homB or homA alone) and between genes in different strains (homB vs homA), considering pairs of homB and homA sequences of 24 Helicobacter pylori strains.

From: Allelic diversity and phylogeny of homB, a novel co-virulence marker of Helicobacter pylori

 

Segment 1 (n = 24)

Segment 3 (n = 24)

 

homBalone a

homAalone a

homBvs homAb

homBalone a

homAalone a

homBvs homAb

Mol. distance (nt)

0.061 ± 0.006&

0.077 ± 0.007

0.113 ± 0.010

0.066 ± 0.005

0.065 ± 0.005

0.064 ± 0.004

Ks

0.199 ± 0.025

0.244 ± 0.026

0.286 ± 0.034

0.209 ± 0.020

0.207 ± 0.020

0.202 ± 0.019

Ka

0.026 ± 0.005

0.030 ± 0.004

0.067 ± 0.011

0.027 ± 0.005

0.025 ± 0.004

0.026 ± 0.004

Ka/Ks

0.131 ± 0.029

0.122 ± 0.021

0.234 ± 0.047

0.129 ± 0.027

0.121 ± 0.021

0.130 ± 0.023

  1. Mol., molecular
  2. nt, nucleotides
  3. Ks, Synonymous substitutions
  4. Ka, Non-synonymous substitutions
  5. &Value ± Standard Error.
  6. a The 24 sequences, totalling 276 comparisons.
  7. b All 48 sequences, totalling 552 comparisons (each homB was compared to each homA, excluding the pairs within the same strain)