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Table 4 Changes of 17 loci during in vitro serial passages

From: Application and evaluation of the MLVA typing assay for the Brucella abortus strains isolated in Korea

Locus Number of passages that showed a change1) Change of the TRs copy number
  B. abortus
544
B. abortus
2308
B. abortus
KBa019
B. abortus
KBa011
 
Bruce 04 28 - 2) - - An increase in one TRs
Bruce 16 28 - - - An increase in one TRs
Hoof 3 29 - - - An increase in one TRs
14 other loci - - - - none
  1. 1) Four strains were sub-cultured to fresh media 30 times by serial passages at two- to three-day intervals
  2. 2) No change after 30 passages