Inhibition of His
-α-IPMS activity by l-leucine. Activity of His6-α-IPMS-2CR and of His6-α-IPMS-14CR in the presence of 0.1–10.0 mM of l-leucine. Assays were performed as described in the Materials and Methods at 37°C, pH 8.5. Each point is the average of three assays and the vertical bars represent the standard deviations.