Figure 2
From: Dxr is essential in Mycobacterium tuberculosisand fosmidomycin resistance is due to a lack of uptake
Efflux pump inhibitors have no effect on mycobacterial resistance to fosmidomycin. Mycobacteria were grown in the presence of 100 μg/ml fosmidomycin (Fos), 12 μg/ml reserpine (RES), 40 μg/ml verapamil (VER) and 1.25 μg/ml carbonyl cyanide m-chlorophenylhydrazone (CCCP) where indicated. (A) M. tuberculosis was grown for 28 d and (B) M. smegmatis for 16 h. Error bars represent standard deviation of triplicate samples.