Homology modeling of EndoS. Panel A, model of amino acids 37–446 of EndoSusing EndoF3 as the template. Glu-235 in the active is shown in red. Panel B, EndoS model (yellow) superimposed in the structure of EndoF3 (blue). Panel C, model of amino acids 446–557 of EndoS using the LRR-region from InlB as the template. Panel A and C, β-strands are shown in yellow, α-helices in purple, and loops in turquoise.