Antibiotic | Â | Changes in colony counts vs initial inocula after | |||||||
---|---|---|---|---|---|---|---|---|---|
 |  | 3 h | 6 h | 12 h | 24 h | ||||
 |  | CO2 | Air | CO2 | Air | CO2 | Air | CO2 | Air |
Telithromycin | 4 × MIC | -1.53 | -1.96 | -2.38 | -2.69 | > -3.0 | > -3.0 | > -3.0 | > -3.0 |
 | 2 × MIC | -0.68 | -0.30 | -1.55 | -1.96 | -2.82 | -2.84 | > -3.0 | > -3.0 |
 | 1 × MIC | -0.38 | -0.56 | -0.88 | -0.66 | -1.23 | -1.27 | -1.66 | -1.37 |
 | 1/2 × MIC | 0.17 | 0.78 | 2.26 | 2.43 | 2.94 | 3.26 | 3.53 | 4.40 |
 | 1/4 × MIC | 0.33 | 0.92 | 2.66 | 2.68 | 3.26 | 3.30 | 3.64 | 4.51 |
 | ELF | -0.55 | -0.92 | -2.85 | -2.89 | > -3.0 | > -3.0 | > -3.0 | > -3.0 |
Clarithromycin | 4 × MIC | -1.68 | -0.96 | -2.02 | -1.96 | > -3.0 | > -3.0 | > -3.0 | > -3.0 |
 | 2 × MIC | -0.16 | -0.62 | -1.16 | -1.38 | -1.70 | -1.99 | > -3.0 | > -3.0 |
 | 1 × MIC | -0.14 | -0.21 | -0.45 | -0.42 | -1.56 | -0.67 | -1.75 | -1.74 |
 | 1/2 × MIC | 0.33 | 0.51 | 1.76 | 1.34 | 1.99 | 1.45 | 3.51 | 4.28 |
 | 1/4 × MIC | 0.64 | 0.75 | 2.87 | 2.88 | 3.44 | 3.35 | 4.03 | 4.61 |
 | ELF | -0.71 | -1.36 | -2.43 | -2.62 | > -3.0 | > -3.0 | > -3.0 | > -3.0 |
Azithromycin | 4 × MIC | -1.55 | -1.62 | -2.50 | -2.76 | > -3.0 | > -3.0 | > -3.0 | > -3.0 |
 | 2 × MIC | -1.16 | -1.37 | -1.90 | -1.96 | > -3.0 | > -3.0 | > -3.0 | > -3.0 |
 | 1 × MIC | -1.01 | -0.56 | -0.90 | -0.89 | -1.68 | -1.06 | -1.78 | -1.59 |
 | 1/2 × MIC | 0.21 | 0.72 | 0.92 | 1.28 | 1.98 | 2.01 | 2.49 | 2.53 |
 | 1/4 × MIC | 0.27 | 0.79 | 2.54 | 2.04 | 3.04 | 3.14 | 3.72 | 4.16 |
 | ELF | -1.12 | -1.40 | -2.57 | -2.73 | -2.83 | > -3.0 | > -3.0 | > -3.0 |
Control | Â | 0.97 | 0.98 | 3.07 | 3.01 | 3.87 | 3.46 | 5.05 | 4.68 |