Figure 5

Biodistribution of ⁶⁴Cu labeled bacteria. The distribution of ⁶⁴Cu labeled F. tularensis subsp. novicida was compared to ⁶⁴Cu labeled K. pneumoniae, ⁶⁴Cu labeled E. coli and ⁶⁴Cu labeled LVS in each tissue at 20 hrs pi. The data represent an average of 3 – 9 mice per infection and are given as %ID/g of tissue. The data obtained for each of the tissues sampled 20 hrs p.i from mice infected with F. tularensis subsp. novicida was compared statistically to the same tissue when inoculated with ⁶⁴Cu labeled K. pneumoniae and E. coli at 20 hrs p.i by using a two tail Student's t-test [e.g. lung (i.n) to lung (i.g)]. * = p < 0.05, ** = p < 0.01 and *** = p < 0.005.