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Table 2 Indices of oxidative stress (with standard deviations) in the ileum mucosa in mice challenged with S. Typhimurium and treated with ofloxacin and/or the probiotic L. fermentum ME-3

From: Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin

Experimental groups

LPO (pmol/mg protein)

GSSG/GSH

Gr1 (ST)

338 ± 461;4

0.26 ± 0.413;5

Gr2 (ST+OFX)

228 ± 412

0.26 ± 0.11

Gr3 (ST+ME-3)

169 ± 111;2

0.16 ± 0.203

Gr4 (ST+OFX+ME-3)

161 ± 271;2

0.17 ± 0.113

Control (PBS)

157 ± 244

0.11 ± 0.25

  1. ST – Salmonella Typhimurium
  2. OFX – ofloxacin
  3. ME-3 – Lactobacillus fermentum ME-3
  4. PBS – phosphate buffered saline
  5. LPO – lipid peroxides
  6. GSSG/GSH – glutathione redox ratio
  7. 1p < 0.001 Gr1 vs Gr3 and Gr4
  8. 2p = 0.002 Gr2 vs Gr3 and Gr 4
  9. 3 p = 0.006 Gr1 vs Gr3 and Gr4
  10. 4p < 0.001 Gr1 vs Control
  11. 5p < 0.003 Gr1 vs Control
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BMC Microbiology

ISSN: 1471-2180

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