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Table 1 The number of mice with viable S. Typhimurium and granulomas in liver and spleen

From: Eradication of Salmonella Typhimurium infection in a murine model of typhoid fever with the combination of probiotic Lactobacillus fermentum ME-3 and ofloxacin

Experimental groups

Number (%) of mice with

 

Salmonella Typhimurium

Granulomas

 

ileum

blood

liver

liver

spleen

Gr1 (ST)

111;2

3

113

164;5

117

n = 20

55%

15%

55%

80%

55%

Gr2 (ST+OFX)

21

1

3

86

07;8

n = 13

15%

8%

23%

62%

 

Gr3 (ST+ME-3)

21

0

13

54

48

n = 13

15%

 

8%

38%

31%

Gr4 (ST+OFX+ME-3)

02

0

0

25;6

07;8

n = 13

   

15%

 
  1. ST – Salmonella Typhimurium
  2. OFX – ofloxacin
  3. ME-3 – Lactobacillus fermentum ME-3
  4. 1 p = 0.032 Gr1 vs Gr2 and Gr3 viable ST in ileum
  5. 2 p = 0.002 Gr1 vs Gr4 viable ST in ileum
  6. 3 p = 0.009 Gr1 vs Gr3 viable ST in liver
  7. 4 p = 0.027 Gr1 vs Gr3 liver granulomas
  8. 5 p < 0.001 Gr1 vs Gr4 liver granulomas
  9. 6 p = 0.023 Gr2 vs Gr4 liver granulomas
  10. 7 p = 0.002 Gr1 vs Gr2 and Gr4 spleen granulomas
  11. 8 p = 0.048 Gr2 vs Gr3 and Gr4 vs Gr3 spleen granulomas
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BMC Microbiology

ISSN: 1471-2180

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