Figure 5

Statistical sequence analysis of predicted Kex2 cleavage sites. (A) sequence logo of cleaved sites and (B) of non-cleaved sites. Position 5 of the logos corresponds to the P1 position in the substrate. Negatively charged residues (red) are overrepresented in processed substrate P1', P2' and P4' positions. Color key: red: negatively charged, blue: positively charged, black: apolar, green: polar.