IS 6110 DNA fingerprint, spoligotype and 24 loci MIRU-VNTR typing patterns of the 97 strains investigated. The position of each IS6110 band is normalized, so that banding patterns of all strains are mutually comparable. The copy numbers of 24 MIRU loci (see Materials and Methods section) are displayed in grey shades ranging from 0 (white) to 14 copies (black). The strains genotypes are ordered in a dendogram based on the similarity of their MIRU-VNTR typing data. In addition resistance to first line drugs is shown by a black box. Abbreviations: WT, wild type; EAI, M. tuberculosis East African Indian; LAM, M. tuberculosis Latin American Mediterranean.