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Table 4 Number of microarray divergent genes averaged by functional class and type of comparison

From: Helicobacter pylori genome variability in a framework of familial transmission

Functional category Number of divergent genes for RAPD type A relative to type B isolates Number of divergent genes for all isolates relative to the reference (26695/J99)
Code: Description Number of genes Mean ± SE1 Percent Mean ± SE1 Percent
1–7, 9–12: Basic functions2 635 23 ± 1 4 42 ± 5 7
8: DNA metabolism 140 17 ± 1 12 44 ± 2 31
13: Cell envelope 165 11 ± 0.3 7 24 ± 1 15
14: Cellular processes 130 9 ± 0.4 7 18 ± 2 14
15: Plasmid- and transposon-related functions 9 5 ± 0.2 56 6 ± 0.3 67
16, 17: Unknown and hypothetical 666 82 ± 2 12 181 ± 7 27
All 1,745 147 ± 4 8 314 ± 16 18
  1. Divergent genes were assessed by microarray for 15 H. pylori isolates, three isolates of RAPD type A (biopsy 15) and 12 isolates of RAPD type B (biopsy 16, 13, 125 and 24a). Divergent genes by functional class were identified for the type A isolates relative to the type B isolates and for all isolates relative to the reference strains.
  2. 1Standard error
  3. 21: Amino acid biosynthesis, 2: Purines, pyrimidines, nucleosides, and nucleotides, 3: Fatty acid and phospholipid metabolism, 4: Biosynthesis of cofactors, prosthetic groups and carriers, 5: Central intermediary metabolism, 6: Energy metabolism, 7: Transport and binding proteins, 9: Transcription, 10: Protein synthesis, 11: Protein fate, 12: Regulatory functions.