Table 2 SNPs in the alkA region
Downstream region | ← ada/alkAb | Upstream region | |||||||
|---|---|---|---|---|---|---|---|---|---|
SNP positiona | SNP1 1471.218 | SNP2 1471.659 | SNP3 1477.028 | Codon 337 1478.108 | Codon 269 1478.312 | Codon 79 1478.883 | Codon 12 1479.085 | Codon 11 1479.088 | SNPs 4, 5, 6 1480.972, 1482.627, 1484.708 |
Strains | In CAR strains | ||||||||
M.tb alkA 79+337 c | wt | C→T | wt | AC T→AA T | wt | TG G→TA G | wt | wt | T→C, T→C, A→C |
M.tb alkA 337 d | wt | C→T | wt | AC T→AA T | wt | wt | wt | wt | T→C, T→C, A→C |
M.bv CAR e | C→T | C→T | wt | wt | wt | wt | A TC→G TC | wt | T→C, T→C, A→C |
in other strains | |||||||||
M.bv AF2122 | C→T | C→T | C→- | wt | CTG→CTA | TG G→TA G | A TC→G TC | wt | T→C, T→C, A→C |
M. bv BCG | C→T | C→T | wt | wt | CTG→CTA | wt | A TC→G TC | wt | T→C, T→C, A→C |
M.tb 210 | wt | C→T | wt | wt | wt | wt | A TC→G TC | G CG→A CG | T→C, T→C, A→C |
M.tb CDC1551 | wt | C→T | wt | wt | wt | wt | wt | wt | T→C, T→C, A→C |
M.tb H37Rv | wt | wt | wt | wt | wt | wt | wt | wt | wt |