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Table 1 Regulatory dependence of type III secreted effectors under SPI-1 inducing conditions.

From: Systematic analysis of the regulation of type three secreted effectors in Salmonella enterica serovar Typhimurium

   A B C D E F G H I
   wild type MM+ pWSK29 MM sprB+ MM hilC+ MM hilD+ MM hilA + MM invF+ sicA + MM ssrB+ MM sirA +
1 sopA-lacZ 7685 ± 1026 23 ± 1 1 ± 2 0 ± 2 1 ± 2 9 ± 3 4982 ± 625 9 ± 3 1 ± 1
2 sopB-lacZ 10981 ± 922 148 ± 11 85 ± 2 75 ± 8 82 ± 4 199 ± 15 56160 ± 4842 3095 ± 1711 113 ± 8
3 sopE2-lacZ 14251 ± 4224 1872 ± 252 2425 ± 748 2477 ± 281 1093 ± 391 3735 ± 65 31415 ± 1109 3963 ± 90 2574 ± 69
4 slrP-lacZ 385 ± 44 305 ± 5 3511 ± 349 295 ± 164 448 ± 78 403 ± 87 1282 ± 138 308 ± 39 621 ± 23
5 sspHl-lacZ 796 ± 196 689 ± 26 697 ± 165 668 ± 98 949 ± 103 960 ± 146 2906 ± 585 827 ± 165 666 ± 67
6 sspH2-lacZ 360 ± 34 326 ± 38 412 ± 128 225 ± 16 389 ± 71 453 ± 90 359 ± 24 15685 ± 1481 296 ± 11
7 sifA-lacZ 21664 ± 538 10321 ± 719 9970 ± 528 9232 ± 665 9611 ± 887 10176 ± 817 10329 ± 1153 14085 ± 429 16738 ± 1612
8 sifB-lacZ 65 ± 2 939 ± 81 1393 ± 849 19 ± 5 1537 ± 470 809 ± 150 30 ± 6 14334 ± 2904 25 ± 6
9 sseI-lacZ 70 ± 4 60 ± 10 69 ± 22 32 ± 2 43 ± 5 61 ± 15 47 ± 10 5154 ± 1291 60 ± 15
10 sseG-lacZ 1931 ± 36 2046 ± 440 1153 ± 257 3001 ± 297 2083 ± 442 2872 ± 314 2444 ± 554 25454 ± 314 919 ± 73
  1. The lac fusion being measured is listed in the left column. The strain background is listed along the top. Each strain harbors a lac fusion to an effector and a plasmid encoding a regulator or the vector control. The values in bold are those showing greater than 3-fold differences compared to the MM + pWSK29 strain that are discussed in the text. Each value represents the mean of at least three experiments ± standard deviation. MM, multi-regulator mutant [Δ(avrA-invH)1 ssrB::cat sirA4::hyg].