Table 1 Reuterin activity and LMW-SH concentration in intestinal bacteria
Organisms | Strainsa | MICb[mM] | MBCb [mM] | LMW-SHc [μmol/1012 cells] |
|---|---|---|---|---|
Escherichia coli | DSM 5698 | 7.5–15.0 | 15.0–30.0 | 7.9 ± 1.3 |
Bacteroides vulgatus | DSM 1447 | < 1.9 | 1.9–3.8 | 1.6 ± 0.4 |
Bacteroides thetaiotaomicron | DSM 2079 | 1.9–3.8 | 1.9–3.8 | -d |
Bacteroides fragilis | LMG 10263 | 3.8–7.5 | 3.8–7.5 | 7.3 ± 1.7 |
Bifidobacterium catenulatum | LMG 11043 | 1.9–3.8 | 7.5–15.0 | 1.8 ± 0.9 |
Bifidobacterium longum | DSM 20219 | 1.9–3.8 | 3.8–7.5 | 1.5 ± 0.5 |
Bifidobacterium longum infantis | DSM 20088 | 1.9–3.8 | 1.9–3.8 | 5.2 ± 0.6 |
Bifidobacterium adolescentis | DSM 20083 | 3.8–7.5 | -d | 1.3 ± 0.1 |
Bifidobacterium bifidum | DSM 20456 | 3.8–7.5 | 7.5–15.0 | 2.4 ± 0.5 |
Bifidobacterium breve | DSM 20213 | 7.5–15 | 7.5–15.0 | 2.0 ± 0.1 |
Lactobacillus acidophilus | ATCC 4356 | 15.0–40.0 | 15.0–40.0 | 10.7 ± 0.3 |
Lactobacillus casei | ATCC 334 | 15.0–40.0 | 40.0–80.0 | 2.0 ± 0.3 |
Lactobacillus fermentum | ETH-Z | 15.0–40.0 | 15.0–40.0 | 2.9 ± 1.2 |
Lactobacillus salivarius | ETH-Z | 15.0–40.0 | 40.0–80.0 | 22.2 ± 5.0 |
Lactobacillus reuteri | DSM 20016 | 30.0–50.0 | 60–120. | 6.5 ± 0.8 |
Lactobacillus reuteri | SD 2112 | 30.0–50.0 | 60–120 | 6.1 ± 1.4 |
Eubacterium biforme | DSM 3989 | 1.9–3.8 | 3.8–7.5 | 3.0 ± 0.7 |
Eubacterium eligens | DSM 3376 | 1.9–3.8 | 1.9–3.8 | -d |
Colinsella aerofaciens | DSM 3979 | 3.8–7.5 | 7.5–15.0 | 21.9 ± 4.3 |
Enterococcus faecium | DSM 20477 | 3.8–7.5 | 30.0–50.0 | 4.8 ± 1.3 |
Streptococcus salivarius | DSM 20560 | 3.8–7.5 | 15.0–30.0 | 9.6 ± 1.1 |
Clostridium difficile | ETH-Z | < 1.9 | 3.8–7.5 | 43.0 ± 3.8 |
Clostridium clostridioforme | DSM 933 | 15.0–30.0 | 15.0–30.0 | 3.1 ± 0.8 |
Ruminococcus productus | DSM 2950 | 7.5–15.0 | 3.8–7.5 | 2.5 ± 0.5 |
Listeria innocua | HPB 13 | 7.5–15.0 | 7.5–15.0 | 5.5 ± 1.4 |
Listeria ivanovii | HPB 28 | 3.8–7.5 | 7.5–15.0 | 1.5 ± 0.6 |