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Table 1 Reuterin activity and LMW-SH concentration in intestinal bacteria

From: Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteria

Organisms Strainsa MICb[mM] MBCb [mM] LMW-SHc [μmol/1012 cells]
Escherichia coli DSM 5698 7.5–15.0 15.0–30.0 7.9 ± 1.3
Bacteroides vulgatus DSM 1447 < 1.9 1.9–3.8 1.6 ± 0.4
Bacteroides thetaiotaomicron DSM 2079 1.9–3.8 1.9–3.8 -d
Bacteroides fragilis LMG 10263 3.8–7.5 3.8–7.5 7.3 ± 1.7
Bifidobacterium catenulatum LMG 11043 1.9–3.8 7.5–15.0 1.8 ± 0.9
Bifidobacterium longum DSM 20219 1.9–3.8 3.8–7.5 1.5 ± 0.5
Bifidobacterium longum infantis DSM 20088 1.9–3.8 1.9–3.8 5.2 ± 0.6
Bifidobacterium adolescentis DSM 20083 3.8–7.5 -d 1.3 ± 0.1
Bifidobacterium bifidum DSM 20456 3.8–7.5 7.5–15.0 2.4 ± 0.5
Bifidobacterium breve DSM 20213 7.5–15 7.5–15.0 2.0 ± 0.1
Lactobacillus acidophilus ATCC 4356 15.0–40.0 15.0–40.0 10.7 ± 0.3
Lactobacillus casei ATCC 334 15.0–40.0 40.0–80.0 2.0 ± 0.3
Lactobacillus fermentum ETH-Z 15.0–40.0 15.0–40.0 2.9 ± 1.2
Lactobacillus salivarius ETH-Z 15.0–40.0 40.0–80.0 22.2 ± 5.0
Lactobacillus reuteri DSM 20016 30.0–50.0 60–120. 6.5 ± 0.8
Lactobacillus reuteri SD 2112 30.0–50.0 60–120 6.1 ± 1.4
Eubacterium biforme DSM 3989 1.9–3.8 3.8–7.5 3.0 ± 0.7
Eubacterium eligens DSM 3376 1.9–3.8 1.9–3.8 -d
Colinsella aerofaciens DSM 3979 3.8–7.5 7.5–15.0 21.9 ± 4.3
Enterococcus faecium DSM 20477 3.8–7.5 30.0–50.0 4.8 ± 1.3
Streptococcus salivarius DSM 20560 3.8–7.5 15.0–30.0 9.6 ± 1.1
Clostridium difficile ETH-Z < 1.9 3.8–7.5 43.0 ± 3.8
Clostridium clostridioforme DSM 933 15.0–30.0 15.0–30.0 3.1 ± 0.8
Ruminococcus productus DSM 2950 7.5–15.0 3.8–7.5 2.5 ± 0.5
Listeria innocua HPB 13 7.5–15.0 7.5–15.0 5.5 ± 1.4
Listeria ivanovii HPB 28 3.8–7.5 7.5–15.0 1.5 ± 0.6
  1. aDSM: Deutsche Sammlung von Mikroorganismen und Zellkulturen, Braunschweig, Germany ATCC: American Type Culture Collection, Rockville, Maryland, USA HPB: Health Protection Branch, Health and Welfare Canada, Ottawa, Ontario, Canada ETH-Z:Culture Collection of the Food Biotechnology Laboratory, ETH Zürich, Switzerland LMG: Belgian Co-Ordinated Collections of Micro-Organisms, Gent, Belgium SD2112 = BioGaia, Stockholm, Sweden
  2. bMIC and MBC data are expressed as the range obtained from at least three independent repetitions for each species
  3. cLMW-SH concentrations are expressed as mean ± SD of at least three independent repetitions
  4. dNot determined