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Table 4 The number of positively selected sites in different functional domains of S protein.

From: Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groups

Functional domain

02–04 interspecies epidemic group

03-early-mid epidemic group

Fisher's exact test (p)

RBD

6

1

 

HR1–HR2

1

4

0.045455

HR2

0

3

0.033333

  1. The Fisher's exact test was performed for HR1–HR2 vs. RBD, and HR2 vs. RBD, respectively.