Table 1 Recombinant ALO ED₅₀ in the absence of serum. Results show amount of rALO necessary for 50% cytolysis of primary human PMNs, lymphocytes, monocyte-derived macrophages, THP-1 monocytes, ME-180, D562, and A549 epithelial cells after 30 min at 37°C. * PMN cytolysis was measured at 10 min. Data derived from Figures 1–5 by cytotoxicity curve extrapolation.

From: The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages