Table 2 This table presents genes that were consistently and statistically up regulated in the hypothetically less pathogenic lineage II strains
From: Microarray based comparison of two Escherichia coli O157:H7 lineages
Name | average mean log ratio (635/532) | average fold increase | One Sample t-Test (p) | definition | accession |
|---|---|---|---|---|---|
inaA | 0.57 | 1.49 | 0.028507 | pH-inducible protein involved in stress response | NP_288811.1 |
nupG | 0.60 | 1.51 | 0.002513 | transport of nucleosides, permease protein | NP_289536.1 |
ompR | 0.61 | 1.53 | 0.019932 | response regulator (sensor, EnvZ) affecting transcription of ompC and ompF: outer membrane protein synthesis | NP_289945.1 |
flgC | 0.62 | 1.54 | 0.008244 | flagellar biosynthesis, cell-proximal portion of basal-body rod | NP_287208.1 |
secD | 0.64 | 1.55 | 0.050195 | protein secretion; membrane protein, part of the channel | NP_286147.1 |
recB | 0.75 | 1.68 | 0.050257 | DNA helicase, ATP-dependent dsDNA/ssDNA exonuclease V subunit, ssDNA endonuclease | NP_289372.1 |
hemY | 0.78 | 1.72 | 0.045026 | a late step of protoheme IX synthesis | NP_290430.1 |
fhuA | 0.79 | 1.73 | 0.015243 | outer membrane protein receptor for ferrichrome, colicin M, and phages T1, T5, and phi80 | NP_285846.1 |
cheB | 0.81 | 1.75 | 0.014779 | response regulator for chemotaxis (cheA sensor); protein methylesterase | NP_288320.1 |
cutC | 0.83 | 1.77 | 0.017209 | Copper homeostasis protein | NP_288311.1 |
secF | 0.96 | 1.94 | 0.033545 | protein secretion, membrane protein | NP_286148.1 |
wecF | 0.97 | 1.95 | 0.021373 | TDP-Fuc4NAc:lipidII transferase; synthesis of enterobacterial common antigen (ECA) | NP_290425.1 |
frdD | 0.97 | 1.95 | 0.042158 | fumarate reductase, anaerobic, membrane anchor polypeptide | NP_290786.1 |
espP | 1.07 | 2.10 | 0.023407 | EspP | NP_052685.1 |
kfras | 1.08 | 2.11 | 0.040371 | KfraS | NP_052633.1 |
etpJ | 1.10 | 2.15 | 0.016101 | EptJ | NP_052615.1 |
toxB | 1.11 | 2.15 | 0.020589 | toxin B | NP_052665.1 |
fliY | 1.11 | 2.16 | 0.001708 | putative periplasmic binding transport protein | NP_288381.1 |
wzx | 1.22 | 2.33 | 0.014144 | O antigen flippase Wzx | NP_288543.1 |
etpH | 1.28 | 2.42 | 0.009559 | EtpH | NP_052613.1 |
etpO | 1.28 | 2.43 | 0.021162 | EptO | NP_052620.1 |
fumC | 1.31 | 2.48 | 0.01514 | a late step of protoheme IX synthesis | NP_290430.1 |
ydeW | 1.34 | 2.53 | 0.001173 | putative transcriptional regulator, sorC family | NP_287642.1 |
etpI | 1.39 | 2.62 | 0.005332 | EtpI | NP_052614.1 |
etpM | 1.57 | 2.98 | 0.000193 | EtpM | NP_052618.1 |
cspD | 1.59 | 3.01 | 0.051261 | cold shock protein | NP_286652.1 |
oppC | 1.60 | 3.03 | 0.009279 | homolog of Salmonella oligopeptide transport permease protein | NP_287488.1 |
usher2 | 1.66 | 3.15 | 0.02289 | putative fimbrial usher protein | NP_287650.1 |
cspC | 1.67 | 3.19 | 0.048484 | cold shock protein | NP_288259.1 |
etpN | 1.68 | 3.20 | 0.015507 | EptN | NP_052619.1 |
etpK | 1.70 | 3.25 | 0.000151 | EtpK | NP_052616.1 |
rpoB | 1.74 | 3.34 | 0.005075 | RNA polymerase, beta prime subunit | NP_290619.1 |
argT | 1.81 | 3.51 | 0.007679 | lysine-, arginine-, ornithine-binding periplasmic protein | NP_288884.1 |
fimberal4 | 1.84 | 3.58 | 0.0179 | putative fimbrial protein | NP_290128.1 |
chaper2 | 1.86 | 3.64 | 0.002084 | putative fimbrial chaperone | NP_287649.1 |
fumA | 1.88 | 3.68 | 0.005453 | fumarase C= fumarate hydratase Class II; isozyme | NP_288046.1 |
etpL | 1.97 | 3.92 | 0.009254 | EtpL | NP_052617.1 |
rpoC | 2.01 | 4.04 | 0.021043 | RNA polymerase, beta prime subunit | NP_290619.1 |
cyoE | 2.11 | 4.31 | 0.027937 | protoheme IX farnesyltransferase (haeme O biosynthesis) | NP_286170.1 |
hscA | 2.32 | 4.99 | 0.012973 | heat shock protein, chaperone, member of Hsp70 protein family | NP_289083.1 |
fimbsub1 | 2.53 | 5.79 | 0.029658 | putative major fimbrial subunit | NP_287648.1 |