Figure 7From: Proteolytic cleavage of pertussis toxin S1 subunit is not essential for its activity in mammalian cellsS1 processing in CHO cell transfectants expressing S1. (A) Western blot showing lack of processing of endogenous S1 in transfectants expressing S1 in the cytosol (S1-SP) or in the ER (S1+SP). (B) Western blot showing EDTA-inhibitable processing of S1 after exogenous addition of purified PT (20 nM) to these transfectants.Back to article page