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Table 2 Expression of HIV receptors and co-receptors in mammary cells exposed to exogenous Tat protein (100 ng/ml)1.

From: Proliferative activity of extracellular HIV-1 Tat protein in human epithelial cells: expression profile of pathogenetically relevant genes

Cell line

CD4

CXCR4

CCR1

CCR2

CCR3

CCR4

CCR5

MCF-7 (untreated)

+

+

-

-

-/+

-/+

-

MCF-7 + Tat

       

1 h

+

++

-

-

+

+

-

3 h

+

++

-

-

++

++

-

6 h

+

++

-

-

++

++

-

MEC-1 (untreated)

+

+

-

-

-/+

-/+

-

MEC-1 + Tat

       

1 h

+

++

-

-

+

+

-

3 h

+

++

-

-

++

++

-

6 h

+

++

-

-

++

+

-

  1. 1. Expression of mRNA transcripts has been evaluated by semi-quantitative RT-PCR as reported in the Materials and Methods section. Transcript expression is reported as negative (-) or positive. Band intensity is indicated with 1+, 2+, or 3+.
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BMC Microbiology

ISSN: 1471-2180

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