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Table 1 Sensor and response regulator molecules at high and low osmolarity. Based on the assumed in vivo data as reported by Cai and Inouye, 2002 [30], the levels of the components EnvZ, OmpR and OmpRP at high and low osmolarity conditions are listed. At high osmolarity 10% of cellular OmpR gets phosphorylated, sufficient enough to promote OmpC expression. Contrarily at low osmolarity only 3.5% of cellular OmpRP would be sufficient enough to activate the expression of OmpF.

From: A simulation model of Escherichia coli osmoregulatory switch using E-CELL system

SUBSTANCE

High osmolarity (no. of molecules/cell)

Low osmolarity (no. of molecules/cell)

EnvZ

100

60

OmpR

3500

2100

OmpRP

350(10%)

70(3.5%)