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Table 2 Results of BEI alphavirus and flavivirus BEI inactivation trials at 37°C

From: Sucrose density gradient centrifugation and cross-flow filtration methods for the production of arbovirus antigens inactivated by binary ethylenimine

Virus Stock Strain PFU/mL Hours for Complete BEI Inactivation Inactivation Rate (Log10 PFU/mL.h-1)
RRV C6/36 T48 2.0 × 107 3 2.4
BFV C6/36 BH2193 1.0 × 108 4 2.0
JEV C6/36 TS00 2.1 × 1011 1 11.3
MVEV C6/36 MRM66 2.5 × 108 2 4.2
ALFV PS-EK MRM3926 1.0 × 108 1 8.0