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Table 2 Results of BEI alphavirus and flavivirus BEI inactivation trials at 37°C

From: Sucrose density gradient centrifugation and cross-flow filtration methods for the production of arbovirus antigens inactivated by binary ethylenimine

Virus Stock

Strain

PFU/mL

Hours for Complete BEI Inactivation

Inactivation Rate (Log10 PFU/mL.h-1)

RRV C6/36

T48

2.0 × 107

3

2.4

BFV C6/36

BH2193

1.0 × 108

4

2.0

JEV C6/36

TS00

2.1 × 1011

1

11.3

MVEV C6/36

MRM66

2.5 × 108

2

4.2

ALFV PS-EK

MRM3926

1.0 × 108

1

8.0

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BMC Microbiology

ISSN: 1471-2180

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