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Figure 3 | BMC Microbiology

Figure 3

From: Restricted changes in major surface protein-2 (msp2) transcription after prolonged in vitro passage of Anaplasma phagocytophilum

Figure 3

ClustalX alignment and consensus amino acid sequences of Msp2 hypervariable domains. Domains were translated from genomic and RT-PCR amplicons of A. phagocytophilum Webster strain msp2 after 7 and 20 passages in vitro. The alignment demonstrates the heterogeneity of the hypervariable domains and the lack of significant similarities that would suggest combinatorial gene conversion as a mechanism for ongoing Msp2 antigenic variation. Paralog names are listed on the left, the total number of amino acid residues is shown on the right; the consensus sequence is shown on the bottom – "." indicates a semi-conserved position, ":" indicates a highly conserved position, and "*" indicates a conserved position.

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