Figure 6

Alignment of MtnX with the consensus of pfam00702 http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00702amp0026;version=v1.54, that includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. Red letters represent identities, blue letters conservative replacements (similarity classes: AGPST, ILMV, FWY, DENQ, HKR). A loop containing a metal (presumably iron, or an iron-sulfur cluster) is likely to be present in MtnX.