Table 2 Minimal inhibition concentration (MIC 90 ) of three statins against the transformants and the original M. circinelloides strain
From: Transcription of the three HMG-CoA reductase genes of Mucor circinelloides
Strains/Statins | Fluvastatin (μg/ml) | Atorvastatin (μg/ml) | Rosuvastatin (μg/ml) |
|---|---|---|---|
MS12 | 4 | 16 | 32 |
MS12 + pNG1 | 4 | 16 | 32 |
MS12 + pNG2 | 32 | 256 | >256 |
MS12 + pNG3 | 64 | >256 | >256 |