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Table 2
Minimal inhibition concentration (MIC
90
) of three statins against the transformants and the original
M. circinelloides
strain
From:
Transcription of the three HMG-CoA reductase genes of
Mucor circinelloides
Strains/Statins
Fluvastatin (μg/ml)
Atorvastatin (μg/ml)
Rosuvastatin (μg/ml)
MS12
4
16
32
MS12 + pNG1
4
16
32
MS12 + pNG2
32
256
>256
MS12 + pNG3
64
>256
>256
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